![]() There is variation in the definition of CSF leakage across different studies. Their efficacy in the prevention of CSF leakage, especially in the pediatric population, however, has not been studied. Surgeons may make use of autologous or synthetic duraplasty material and may choose to use a sealant. Watertight closure is thought to be the most important step to prevent postoperative CSF leakage. In addition, it is associated with increased healthcare costs. ![]() CSF leakage may necessitate invasive treatment, such as surgical wound revision, and prolong hospitalization. The complications associated with CSF leakage include wound infection, meningitis, and CSF hypotension. ![]() Nevertheless, the clinical consequences with respect to secondary complications such as infection and the necessity for invasive treatment are serious.Ĭerebrospinal fluid leakage is a potentially serious complication after intradural spinal surgery. ConclusionsĬSF leakage after intradural spinal surgery in the pediatric population is relatively rare (2.7%). SSI occurred in 10.7%, which included both cases of CSF leak. In total, 1 patient developed a PMC without a CSF leak which was treated with wound revision surgery. One patient was treated with a pressure bandage and an external lumbar drain on day 4 after diagnosis of the leak, and the other was treated with wound revision surgery on day 1 after the leak occurred. It occurred on days 3 and 21 after the index procedure, respectively. CSF leakage occurred in 2.7% (2/75) of procedures. The median age in this cohort was 5 (IQR = 0-13 years. We included a total of 75 procedures, representing 66 individual patients. Secondary outcome measures included the presence of pseudomeningocele (PMC), meningitis, and surgical site infection (SSI). The primary outcome measure was CSF leakage within six weeks after surgery, defined as leakage of CSF through the skin. Patients who died or were lost to follow-up within six weeks after surgery were excluded. Patients of 18 years or younger who underwent intradural spinal surgery between 20 in three tertiary neurosurgical referral centers were included. This study aimed to establish the incidence of CSF leakage in children and associated complications after intradural spinal surgery in three tertiary neurosurgical referral centers and to describe the treatment strategies applied.
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